Nobel Prize Winner's Notebooks Windows on Laboratory Life

[Katrina Dean]

In the Melbourne winter of 1935 Frank Macfarlane Burnet, Head of the Virology Department at the Walter and Eliza Hall Institute (WEHI) felt himself coming down with a cold. Instead of drinking a cup of tea or going home to lie down, he took a sample of his nasal mucous and tried to establish the virus on the outside layer of a chick egg embryo. This was Burnet’s technique for growing and studying viruses that he developed as a research fellow a few years earlier at the National Institute for Medical Research in London. A model of this technique as well as Burnet’s notebook is on display at the Melbourne Museum as part of its Biomedical Breakthroughs exhibition until 22 January 2017. Burnet’s sketches in the notebook depict the replication of a cold virus and he notes the end of the experiment, contaminated by a staphylococcus bacterium. The propensity of experiments to fail, for the wrong organisms to grow, or uncertainty about what was being looked at are just a few of the practical insights into laboratory life gained from Burnet’s notebooks.Continue reading here